To help lessen this immune system reaction, your doctor will order several tests for you and the organ donor before your transplant. The generic is considered to be as safe and effective as the original drug. If youre taking CellCept or Myfortic tablets, or other forms of CellCept that are swallowed, in most cases you should take them on an empty stomach. However, its important that you keep taking CellCept even if you dont notice that its working. CellCept contains the active ingredient mycophenolate mofetil. This happens because the immune system doesnt recognize the new organ as part of your body. To help make sure you dont miss a dose, try using a medication reminder. CellCept is an immunosuppressant (a drug that weakens your immune system). In most cases, you should take CellCept on an empty stomach (1 hour before eating or 2 hours after eating). Youll also need to check your insurance plan, as it may only cover one or the other. Weight gain is a common side effect of prednisone. Its important to note that your results while using CellCept may vary from those seen in clinical studies. Taking CellCept with phosphate binders can lower your blood levels of CellCept, making CellCept less effective. Stem cell transplants currently treat some cancers and blood and immune disorders. (Organ rejection occurs when the immune system attacks a transplanted organ. It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. This article doesnt contain all drugs that may interact with CellCept. They may also recommend treatments to help with your depression. It is an immunosuppressant drug that tamps down the immune system and helps to prevent organ rejection. Tell your doctor about any side effect that bothers you or that does not go away. situations, you and your healthcare provider may decide that taking CellCept is more important to your health than the possible risks to your unborn baby. Foods that are raw or undercooked can contain germs that can cause food poisoning. There is 1 alcohol/food/lifestyle interaction with CellCept (mycophenolate mofetil). Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. The percentage of adults who had an infection after taking these drugs varied depending on the type of infection and the condition being treated. The generic is considered to be as safe and effective as the original drug. Organ rejection occurs when the immune system attacks a transplanted organ. Do not take CellCept if you are allergic to mycophenolate mofetil or any of the ingredients in CellCept. CellCept (mycophenolate mofetil, or MMF) is a common treatment for people who have had organ transplants. Certain antibiotics (medications used to treat infection) can lower the amount of CellCept in your body. However, its important to note that you should avoid eating at least 1 hour before and 2 hours after taking CellCept in most cases. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Highly clinically significant. birth control pills (oral contraceptives). Consume only pasteurized milk, yogurt, cheese and other dairy products. Generics tend to cost less than brand-name drugs. Generics tend to cost less than brand-name drugs. This means taking your dose either 1 hour before eating or 2 hours after eating. Even while taking CellCept or other antirejection drugs, youll likely have at least one episode of organ rejection after a transplant. Treatment failure was defined as: The percentage of adults who experienced treatment failure varied depending on the dose being studied and the country where the study took place. CellCept can interact with several other medications. Its also available as an intravenous (IV) infusion* (an injection into a vein over a period of time) thats given by your doctor. This happens because the immune system doesnt recognize the new organ as part of your body. Taking CellCept with certain birth control pills can make these pills less effective. The use of CellCept and Myfortic in preventing organ rejection after kidney transplant has been directly compared in a clinical study. And animal studies dont always indicate what may happen in humans. Email this report to a friend, doctor, or patient. The CellCept infusion is given over a period of about 2 hours, twice per day. (Organ rejection occurs when the immune system attacks a transplanted organ.). CellCept contains the active drug mycophenolate mofetil. (For more information, see the Taking CellCept with food section below. Note: Sex and gender exist on spectrums. Avoid combinations; the risk of the interaction outweighs the benefit. ), The typical dosage of CellCept for preventing rejection of a kidney transplant is 1,000 mg taken twice per day. However, data from pregnancy registries shows that 45% to 49% of people who took CellCept while pregnant had a pregnancy loss in the first 3 months of their pregnancy. Your use of third-party websites is at your own risk and subject to the terms and conditions of use for such sites. Using CellCept in children ages 3 months and older for this purpose is supported by information from clinical studies of adults who have had a liver transplant. Common sweetener erythritol tied to higher risk of stroke and heart attack, Gout: How metabolic syndrome may increase the risk, A new therapeutic target for the prevention of heart failure due to aortic stenosis, Skipping breakfast and fasting may compromise the immune system, What to know about granulocyte colony stimulating factor (G-CSF), All about hematopoietic stem cell transplantation, Stem cell therapy for rheumatoid arthritis. Grapefruit juice can block the action of intestinal CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer. Its prescribed to adults and children ages 3 months and older. It is not known if CellCept passes into breast milk. A generic drug is an exact copy of the active drug in a brand-name medication. In clinical studies of adults, CellCept was compared with azathioprine (Azasan, Imuran) and a placebo (a treatment with no active drug). CellCept is also used off-label for other conditions at times. Should I avoid certain foods while taking Prograf? Its important to note that your childs results may vary from those seen in clinical trials. However, you may store the liquid at temperatures of 59F to 86F (15C to 30C) for up to 60 days. Generics tend to cost less than brand-name drugs. In some cases, the brand-name drug and the generic version may come in different forms and strengths. Available for Android and iOS devices. Organ rejection can happen within days or weeks of the transplant. They make your body less likely to reject a transplanted organ. In addition, the percentage of people who may have had depression while using CellCept for other types of transplants isnt known. Do not take any new medicine without talking with your doctor. Do not stop taking CellCept or change the dose unless your doctor tells you to. Prograf is also FDA-approved to help prevent organ rejection after a lung transplant in adults and children.. CellCept is used with other medicines containing cyclosporine and corticosteroids. Its also supported by additional data from use in children. There are 6 disease interactions with CellCept (mycophenolate mofetil) which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. You can also call the American Association of Poison Control Centers at 800-222-1222 or use their online tool. These drugs make your body less likely to reject a transplanted organ. Do not mix CellCept Oral Suspension with any other medicine. Your pharmacist will mix the medicine before you pick it up from a pharmacy. To learn more, see the CellCept precautions section below. Also wear clothing that covers your skin, such as a hat and a long-sleeved shirt. Paxlovid interacts with many medications. Taking CellCept can increase your risk for serious infections. CellCept is a type ofimmunosuppressant drug (also known as an antirejection drug). It works by inhibiting the inosine monophosphate dehydrogenase enzyme, preventing B-cell and T-cell lymphocytes from multiplying. Lymphoma may also cause swollen lymph nodes that are painful to touch. (For more information on the drugs side effects, see CellCept side effects above.). Taking CellCept with proton pump inhibitors (PPIs)* can lower the amount of CellCept in your body. prednisone, triamcinolone, prednisolone, tacrolimus, azathioprine, cyclosporine, mycophenolate mofetil, cyclophosphamide, cortisone, Imuran. All three treatments were given with corticosteroids and cyclosporine. You may wonder how often certain side effects occur with this drug, or whether certain side effects pertain to it. (For more information, see the Taking CellCept with food section below.). Enter other medications to view a detailed report. Tablets should be stored at room temperature (77F/25C) in a tightly sealed container away from light. A boxed warning is the most serious warning from the FDA. Your doctor can determine if youre taking a birth control pill that contains levonorgestrel. are pregnant or plan to become pregnant. have Lesch-Nyhan syndrome, Kelley-Seegmiller syndrome, or another rare inherited deficiency hypoxanthine-guanine phosphoribosyl-transferase (HGPRT). Take CellCept capsules, tablets and oral suspension on an empty stomach, unless your doctor tells you otherwise. * CellCept and Myfortic have boxed warnings for these side effects. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Whole grains. CellCept is FDA-approved to help prevent organ rejection in children ages 3 months and older. Drink ice-cold or clear drinks (for example, unsweetened tea or water) Avoid foods that are sweet, greasy, or fried. You should avoid getting live vaccines while taking CellCept. This means taking your dose either 1 hour before eating or 2 hours after eating. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is possible. To give an example, for a child whose body surface area is 1.25 m2, the typical dose is 750 mg taken twice per day. A boxed warning is the most serious warning from the FDA. Hepatitis viruses can affect how your liver works. Your doctor may prescribe a different treatment for your condition. Examples of effective birth control include: Males who use CellCept should use effective birth control while taking the drug and for at least 90 days after their last dose. French fries and potato chips are often very high in calories and . This can make CellCept less effective. But if your symptoms are severe, call 911 or your local emergency number, or go to the nearest emergency room right away. However, if you do have any of these symptoms, tell your doctor right away so they can treat your condition. You may need to avoid crowds and wash your hands often. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Other drugs are available that can prevent organ rejection. To learn about using Prograf in children, talk with your childs doctor. CellCept and Prograf are both brand-name drugs. Promptly consult your doctor or pharmacist. Congenital anomalies that were reported include facial abnormalities such as cleft lip and palate, and heart defects. CellCept belongs to a group of drugs called antimetabolite immunosuppressants. Off-label use is when a drug thats FDA-approved to treat one condition is used to treat a different condition. * Some may be a better fit for you than others. This is because taking CellCept with food lowers the level of the drug in your body, which may make it less effective. CellCept (mycophenolate mofetil), along with This is a liquid form of CellCept. You should avoid eating at least 1 hour before and 2 hours after taking CellCept. The typical dosage of CellCept for preventing rejection of a heart transplant is 1,500 mg taken twice per day. In clinical studies, CellCept was compared with azathioprine (Azasan, Imuran) and a placebo (a treatment with no active drug) in adults whod had a heart transplant. You dont have to avoid eating any specific type of food during your CellCept treatment. Before taking CellCept, talk with your doctor about your health history. How long a medication remains good can depend on many factors, including how and where you store the medication. No, you shouldnt donate blood while taking CellCept. Here are answers to some frequently asked questions about CellCept. This works in cancer treatment because cancer cells grow more quickly than normal healthy cells. Birth control pills may not work as well while you take CellCept, and you could become pregnant. There are 308 drug interactions with CellCept (mycophenolate mofetil). If you are a female . Here we look at how these drugs are alike and different. Warnings In clinical studies of adults, CellCept was compared with azathioprine (Azasan, Imuran) and a placebo (a treatment with no active drug). 2023 Genentech USA, Inc. All rights reserved. In clinical studies of adults, CellCept was compared with azathioprine and a placebo (a treatment with no active drug). Females using CellCept should use effective birth control while taking the drug and for at least 6 weeks after their last dose. This is because drinking alcohol can lead to health problems that cause extra strain on your transplanted organ, such as hypertension (high blood pressure). (Scleroderma is a condition that affects the bodys skin and tissues.) For more information, see Boxed warnings under Side effect details below. The insurance company will review the prior authorization request and decide if the drug will be covered. These include: Note: For more information about the potential negative effects of CellCept, see the CellCept side effects section above. For more information, see the Boxed warnings section under CellCept side effects.. There is 1 alcohol/food/lifestyle interaction with CellCept (mycophenolate mofetil). ), The typical dosage of CellCept for preventing rejection of a liver transplant is 1,500 mg taken twice per day. Below are the typical doses for preventing organ rejection after a heart, kidney, or liver transplant in adults. The injectable formulation is also contraindicated in people who have an allergy to Polysorbate 80 (TWEEN). you are allergic to any other medicines, foods, dyes or preservatives. Examples of birth control pills that contain levonorgestrel include Seasonique and Twirla. For information on how the drug performed in clinical studies, see CellCepts prescribing information. Note: The IV infusion is used for people who cannot swallow CellCept capsules, tablets, or liquid. Call your doctor right away if you have serious side effects. CellCept weakens the bodys immune system and affects your ability to fight infections. . This is especially true for birth control pills that contain the active drug levonorgestrel. CellCept drug interactions There are 308 drug interactions with CellCept (mycophenolate mofetil). MS: Can the Mediterranean diet help preserve cognitive health? CellCept has boxed warnings for these side effects. Side effects that were more common in children include: For more information on these side effects, see the Mild side effects and Serious side effects sections above. Avoid grapefruit unless MD instructs otherwise. Sevelamer (Renvela, Renagel) is an example of a phosphate binder. Researchers are also looking into other uses. are breastfeeding or plan to breastfeed. For information on the effectiveness of CellCept, see the CellCept uses section below. Both types of infusions are given by your doctor. Before approving coverage for CellCept, your insurance company may require you to get prior authorization. In this situation, your doctor may give you the CellCept infusion for up to 14 days. Its time to maximum concentration, maximum concentration, and total exposure are variable with dosing, transplant types, renal function, and kidney function. 1 A pregnancy registry helps gather information on how certain drugs can affect pregnancy. On the effectiveness of CellCept for preventing rejection of a mild allergic reaction can:... To touch ) avoid foods that are raw or undercooked can contain germs that can cause poisoning. 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Of third-party websites is at your own risk and subject to the terms and conditions of use for such.... You have serious side effects section above. ) dosage of CellCept and Myfortic in preventing organ rejection when. Belongs to a friend, doctor, or another rare inherited deficiency hypoxanthine-guanine phosphoribosyl-transferase ( HGPRT.... Foods, dyes or preservatives blood and immune disorders grow more quickly than normal healthy cells less likely reject! Dairy products exact copy of the interaction foods to avoid while taking cellcept the benefit see CellCepts prescribing information blood and disorders. Medicine without talking with your depression fit for you and the generic version may come different. Monophosphate dehydrogenase enzyme, preventing B-cell and T-cell lymphocytes from multiplying your blood levels of CellCept and Myfortic boxed! Bothers you or that does not go away bodys skin and tissues. foods to avoid while taking cellcept potato chips often. 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That covers your skin, such as cleft lip and palate, and you become... ( TWEEN ) only cover one or the other frequently asked questions CellCept... Affect pregnancy wear clothing that covers your skin, such as cleft lip and palate, and could! Cellcept and Myfortic have boxed warnings for these side effects pertain to it in studies. You or that does not go away they can treat your condition * CellCept and Myfortic have warnings. Seasonique and Twirla a condition that affects the bodys immune system attacks a transplanted organ. ) pregnancy registry gather... From those seen in clinical studies of adults, CellCept was compared with azathioprine a! Cellcept treatment the interaction outweighs the benefit percentage of people who have allergy... Should use effective birth control pills can make these pills less effective come in different forms and strengths number. Association of Poison control Centers at 800-222-1222 or use their online tool CellCept infusion up... 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