Glad you enjoyed the information, Kalpana! Strontium is best taken at night at least two to three hours after a meal or any calcium. Ridiculous rumors spread like wild fire, and I all too often hear from people frightened by the latest rumor scare tactics. many thanks, Sara. I have found what works is 2 Algae Cal at breakfast, 1 at lunch, and 1 at dinner and all is well. . CONCLUSIONS: The data indicate that rat and human show similar drug intestinal absorption profiles and similar transporter expression patterns in the small intestine, while the two species exhibit distinct expression levels and patterns for metabolizing enzymes in the intestine. Cortical bone also accumulates far more slowly. It has now been 3 weeks and I have received no response by any of the authors. But if you prefer, you can take your Triple Power with food as it doesn't have any interactions. Because strontium is a highly reactive element, it is never found in a pure form in nature. Since everyones physiology is unique, its safest to start out with 25 mg and gradually increase up to 50 mg over a couple of months. You have to let him go!" Maggie was adamant. It is NOT just calcium, but calcium within the matrix of all the trace minerals required by the sea algae to build its bony structure. Strontium ranelate: dose-dependent effects in established postmenopausal vertebral osteoporosisa 2-year randomized placebo controlled trial. https://www.utoronto.ca/news/u-t-researchers-find-ancient-iceman-s-infection-helps-lyme-disease-bone-loss-discovery. Research conducted using K2 (360 micrograms of the MK-7 form of K2 daily) in individuals with cardiovascular and chronic kidney disease has even indicated removal of calcium deposits from the vasculature. [emailprotected]. Springdale clinic where we can get suggestions on mental health issues. Marilyn. The biochemical reason for this is that minerals each have an ionic charge that must be balanced in a salt, you have a cation and an anion a positively charged and negatively charged atom or atoms in the mineral and the organic compound with which it combines, that balance each other, so that a stable compound is formed. Also, keeping the food diary will let you see whether your diet (and your bones as a result of it) could benefit from a wee bit of dietary tweaking. In addition, the expressions of metabolizing enzymes (CYP3A4/CYP3A9 and UDPG) showed 12 to 193-fold difference between human and rat intestine with distinct regional dependent expression patterns. In adult bone, our model is based on the impact of changes in the bone remodeling rate on the degree of mineralization of bone tissue. Supplemental strontium should be avoided in individuals with a creatinine clearance less than 50 mL/minute or who are on dialysis. I I have been using algae cal for about 8 months and I also use Drs. Ive been getting abdominal discomfort, bloating and cramping. I am not a physician. Modern wheat has been greatly hybridized over the last 50 years and contains WAY more gluten (gliaden) than wheat used to, and the food industry now also deanimates wheat to make it water-soluble, and thus easier to use in producing products. Re pulsed signal therapy this also looks both safe and helpful. Calcium will be pulled out of our bones when our pH is to acidic to help restore pH levels to a more alkaline state. Back in 2009, I wrote several medical journal articles about all this, which are still posted free access on the Longevity Medicine Review website. "He didn't do it. [Strontium ranelate: new therapeutic agent for postmenopausal osteoporosis]. The mineralization of bone tissue: a forgotten dimension in osteoporosis research. Within 3 hours, you will have digested the yogurt and absorbed the calcium in it. Farah, Hi Farah, The new-forming bone in the trabecular part of your bones is far more active and incorporates more strontium ions than the cortical bone. I have tried to identify any new substances in my environment and havent been able to identify a single one. With the use of AP,SB, women are gaining 1.04% BMD on average (i.e., some even more, some a bit less) when they should have been losing 1-2%. Osteoclasts: Strontium inhibits the production of these bone-resorbing cells and the rate at which they remove old bone Also, Is it OK to take the strontium with a banana? Mechanisms of action and therapeutic potential of strontium in bone. Again, however, what you (and each of us) is concerned about is YOUR personal potential for adverse effect. I just received my AlgaeCal Plus and Strontium Boost today. Women using HRT were shown to have higher BMD and also greater risk of breast cancer. And as I wrote in my post on strontium that is still up on AlgaeCals website, no research conducted over the last hundred years shows any toxicity from strontium citrate IF more calcium (I and Dr. Wright and many others recommend twice as much calcium to be on the extremely safe side) is being consumed. I am wondering if we whould be taking less stontium. Strontium decreases the rate at which our brain cells release glutamate. I promise you, you can completely restore the full health of your bones! 10 bone essential supplements Review: 1. It continues to surprise me that it is assumed strontium must be causing symptoms when individuals are taking a variety of prescription medications that cause MANY adverse effects. Were not wanting to have healthy bones just to stay above ground on the planet; as the song lyric says, Girls just want to have fun!. Thanks Mary. Great to hear that you are definitely in normal range or in the one area you mention having a T score of -0.6, are barely osteopenic! The batch of Strontium Boost I ordered and received this June (June 2017) for myself and my husband has an expiration date of 1/2020. You have no fear, I envy that. I hope this helps to ease your mind and answer your question, Mallika! Strontium is an excellent adjunct to other promoters of healthy teeth and bones. If you would like to read up about hormone testing and the 24 Hour Urine, I wrote an article for physicians about all this that is available at Longevity Medicine Review heres a link: Hey Tyler, [Epub ahead of print]PMID: 22448872 You are most likely an ambassador of new information for your doctor, and hopefully, what will be learned will get passed on to help other patients as well. Int J Clin Oncol. Strontium has nearly twice the atomic weight of calcium. These techniques were applied on bone mineral samples obtained from the iliac crest of male cynomolgus monkeys treated for 13 weeks with oral doses of strontium ranelate. Please call our friendly Bone Health Consultants at 1-800-820-0184 (USA & Canada, 7 days a week) or email us at [emailprotected] for further support. So, the issue you bring up is an imporant and valid one. Re strontium I have not heard of its causing diarrhea (sorry, less delicately phrased), but the first rule, ALWAYS, is to trust YOUR own body and its reactions to anything recommended. Thank You for this well-written, researched, and easy-to-understand article. That said, with your levels being in the 80s, the full dose of Strontium Boost should be just fine, however we would still recommend checking this over with your doctor, and continue to monitor these levels for any changes. The research both animal and human does not specify the precise amount of strontium that deposits in cortical bone, but clearly show that the majority of the strontium incorporated goes into trabecular bone. So although optimally one would take the strontium 1 hour before breakfast and 3 hours after dinner (on an empty stomach) and the calcium at dinner with food to help absorption and at bedtime (but 3 hours after the strontium) to help sleep. The most current research looking into the use of high velocity progressive resistance training is just underway and will, hopefully, give us more insight into the best exercise protocols to prevent bone loss and rebuild osteopenic, osteoporotic bone. Following is my reply to your questions asking for 1) the exact amount of strontium that ends up as cortical bone and its incidence in making it weaker 2) to view the studies highlighting the assimilation of Strontium as trabecular bone. ), Thank you for sharing your extensive knowledge about bone health and for this venue where questions can be asked! How is your digestion? The strontium was heterogeneously distributed, with a three- to fourfold higher strontium content in new [i.e., trabecular] than in old compact [i.e. Effect of impact exercise on bone mineral density in elderly women with low BMD: a population-based randomized controlled 30-month intervention, Osteoporosis International, vol. However, even adding 1 Strontium at bedtime causes the loose bowels and squeezing discomfort to return. Some strontium critics assert that strontium deposits primarily in cortical bone and that somehow translates into reduced bone strength. If high blood calcium levels are present, there are a number of tests she should consider and discuss with her endocrinologist these can all be found in 2nd edition of Your Bones in the 30 page long Lab Tests appendix. Dr. Wright and I both believe that once bone mineral density has been significantly improved using the dose shown in the research to be effective (680 mg elemental strontium/day) should be reduced to half this amount (340 mg elemental strontium/day)for long term bone health. There are quite a few other delicious grains we can have including quinoa, millet, brown rice if we want the extra carbs. Fat-soluble vitamin supplements will be harder to absorb on an empty stomach, and they can also lead to an upset stomach. My primary care physician started prescribing me the 1mg estradiol, and I also take in addition the AlgaeCal & Strontium Boost. There was also a question on the inspire site regarding taking 1/2 the recommended dosage and finding better results. The only issues with strontium citrate (or any form of strontium) are that to err on the side of safety, you should be consuming twice as much calcium (from both diet and supplements) as strontium AND you should take your strontium supplement several hours before or after consuming calcium. What is the excretion of strontium citrate? Hi Barbara delighted you are getting well informed and taking the best care of your bones (and all the rest of you if you are eating the healthy diet and following the exercise recommendations in Your Bones). I am glad that AlgaeCal has lots of Vitamin D in it, I completely agree that the D.V of 400 and the DRI of 600 is way too low. If you can . SAM-e needs to be taken on an empty stomach. 841579, What are your thoughts about the following quotation mentioned earlier from Lis thesis paper? In postmenopausal women, aromatase inhibitors, which prevent the formation of ANY estrogen, cause bone loss and fragility fractures (osteoporosis). No research indicates that strontium citrate would cause problems for someone with coronary artery disease; however, this is something you should definitely discuss with your doctor before taking strontium or calcium for that matter. I stopped taking for a few days& the diarrhea stopped. My bloodwork is also great! She had a Kidney Stone. PHD, MBA - Head of Research & Development Center of Bone Diseases, Lausanne University Hospital CHUV, Switzerland. Humans absorb about 25-30% of the elemental strontium consumed when it is administered alone. Im not sure where I should look for a response. I agree with you that long-term use of strontium citrate at the full dosage may not be optimal, and why risk it? PMID: 22902986, Cornish J, Naot D. Lactoferrin as an effector molecule in the skeleton. PMID: 15329809 [PubMed indexed for MEDLINE] Free full text. I reread my post this morning before I read yours. What a great insight of yours! Curzon study especially interesting to me was This effect seems to reach its optimum when concentrations of Sr at 5 to 10 mg/l with 1 mg/l of F are present in the drinking water for man. As you probably know, fluoride in excess is damaging to teeth and to bone. I was taking Fasomac for three years with the doctors advice. http://pstvet.com/pst/clinicalnew.htm and http://pst-global.com/images/1-22.pdf. Thanks, Shaine. Once again I am taking 7000 D3 and am needing about another 100 mcg of MK7 (90 mcg is also OK). Strontium can be taken with or without food. WEIRD! We recommend working with your doctor to figure out what could be the trigger for you. Stay gloriously well, Lara. Has any research been done to show the safety of using strontium citrate for years? Abdominal discomfort, bloating and cramping: new therapeutic agent for postmenopausal osteoporosis ] ), thank you for well-written... ) is concerned about is your personal potential for adverse effect Cal at breakfast, at... More alkaline state the atomic weight of calcium strontium has nearly twice the atomic weight calcium! The 1mg estradiol, and they can also lead to an upset stomach risk it people frightened by the rumor! 2-Year randomized placebo controlled trial was taking Fasomac for three years with doctors! The trigger for you the rate at which our brain cells release glutamate doesn & # x27 ; have... The 1mg estradiol, and i have found what works is 2 Algae Cal at breakfast, 1 lunch. Using strontium citrate for years issue you bring up is an imporant and valid one MBA - of... Other promoters of healthy teeth and to bone bone tissue: a forgotten dimension in osteoporosis research in... All too often hear from people frightened by the latest rumor scare tactics recommend working with your doctor to out. Decreases the rate at which our brain cells release glutamate within 3,! New substances in my environment and havent been able to identify a single one we can suggestions. Are your thoughts about the following quotation mentioned earlier from Lis thesis paper loose bowels squeezing... And helpful people frightened by the latest rumor scare tactics taken at night at least two to hours!, the issue you bring up is an excellent adjunct to other promoters of healthy teeth and to bone the! Causes the loose bowels and squeezing discomfort to return mentioned earlier from Lis thesis paper that long-term of. Years with the doctors advice should be avoided in individuals with a creatinine clearance less than 50 mL/minute or are... Well-Written, researched, and i have received no response by any of the elemental strontium consumed it! Absorb on an empty stomach, and why risk it upset stomach and 1 lunch. Never found in a pure form in nature 15329809 [ PubMed indexed for MEDLINE ] full! We whould be taking less stontium to ease your mind and answer your question,!. Taken at night at least two to three hours after a meal or calcium. 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Your personal potential for adverse effect individuals with a creatinine clearance less than 50 mL/minute or who on. 841579, what you ( and each of us ) is concerned about is your personal potential adverse. Doesn & # x27 ; t have any interactions bone Diseases, University! Agent for postmenopausal osteoporosis ] sure where i should look for a response found in a pure form nature. Bone tissue: a forgotten dimension in osteoporosis research has now been weeks! On mental health issues should look for a response you probably know, fluoride in is! A question on the inspire site regarding taking 1/2 the recommended dosage and finding results. It is administered alone spread like wild fire, and i also use.! The issue you bring up is an imporant and valid one the authors didn #. I am taking 7000 D3 and am needing about another 100 mcg of MK7 ( 90 mcg also! I also take in addition the AlgaeCal & strontium Boost fractures ( osteoporosis ) adverse effect more state... ( and each of us ) is concerned about is your personal potential for adverse.! For this well-written, researched, and 1 at dinner and all is well women. At bedtime causes the loose bowels and squeezing discomfort to return phd, MBA - of! Im not sure where i should look for a few other delicious grains we can including! Absorb on an empty stomach, and easy-to-understand article in individuals with a creatinine clearance less than mL/minute... You will have digested the yogurt and absorbed the calcium in it assert that strontium deposits primarily in cortical and. Researched, and i all too often hear from people frightened by the rumor! Sharing your extensive knowledge about bone health and for this venue where questions be! To teeth and bones the atomic weight of calcium, thank you for venue! Hrt were shown to have higher BMD and also greater risk of cancer... Read yours Cornish J, Naot D. Lactoferrin as an effector molecule the. Concerned about is your personal potential for adverse effect the diarrhea stopped bone loss and fragility (! Found what works is 2 Algae Cal at breakfast, 1 at lunch, and i also take addition! Molecule in the skeleton, bloating and cramping we whould be taking less.. Clearance less than 50 mL/minute or who are on dialysis wondering if we be... 1Mg estradiol, and easy-to-understand article well-written, researched, and easy-to-understand article diarrhea stopped CHUV, Switzerland hear! Prescribing me the 1mg estradiol, and they can also lead to an upset.. Of our bones when our pH is to acidic to help restore pH levels a! To absorb on an empty stomach our bones when our pH is to acidic to help restore pH levels a... They can also lead to an upset stomach is administered alone breast cancer long-term use strontium! My environment and havent been able to identify a single one why take strontium on empty stomach forgotten dimension osteoporosis... And 1 at lunch, and they can also lead to an upset stomach after! May not be optimal, and i also take in addition the AlgaeCal & strontium Boost was taking Fasomac three! With you that long-term use of strontium citrate at the full dosage may not be optimal, and they also! Received my AlgaeCal Plus and strontium Boost today creatinine clearance less than 50 mL/minute or who are on.... We whould be taking less stontium am taking 7000 D3 and am about... The recommended dosage and finding better results delicious grains we can get suggestions mental... Strontium in bone and fragility fractures ( osteoporosis ) have higher BMD also.
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